Research

Dr. Chan’s Research Interest:

Genomic in Public Health and Medicine. Population-based genetic testing in infants for metabolic disorder and genetic diseases before the manifestation of symptoms can improve survival and save lives.  Using mathematical models to evaluate the cost and benefits of implementing a population-based newborn screening program are important to guide policy recommendation and allocation of resources.  Since the publication of the methods (Chan and Puck, 2005), the states of Wisconsin and Massachusetts adopted the assay to screen for babies for severe combined immunodeficiency (SCID).  In our research group, we plan to develop models to balance the benefits and harms of expanding genetic screening and the impact of new screening recommendations on the delivery of child health services.